A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the ...

Researchers found that the stereochemistry of lipids like ALC-315 affects mRNA drug safety and efficacy, offering a path to better, safer LNP-based therapies. To deliver therapeutic nucleic acids like ...

For the first time in 50 years, researchers say they have identified a new category of stereoisomers (Nat. Chem. 2018, DOI: 10.1038/s41557-018-0043-6). The new class is characterized by a bond-angle ...

Sometimes conformity is a good thing. Particularly when it comes to stereochemistry. While stereocenters arise in mirror-image enantiomer pairs when left to their own devices, the enantiomers can have ...

An educational escape activity was developed, embedding elements of both augmented and immersive virtual reality technologies, in an active learning environment. The mental visualization of abstract ...

This receptor recognises a preferred octanal conformation, Ryan’s team has shown. He suggests that this receptor binds various aldehydes, ‘then waits to see what shapes the ligand chain can adopt ...

Proteins are made up of long chains of amino acids, and most proteins have one or more of the sulfur-containing amino acid methionine. Oxidation of the sulfur atom in methionine is an important ...

Oxidation of the sulfur atom in methionine is an important biomolecular reaction that can have a wide range of biological consequences depending on the context and the protein involved. Chemists have ...

Chemists at Münster University develop a synthetic method providing access to different stereoisomers of a molecule / Study published in “Nature Catalysis” Just as our left hand is not superposable to ...

An efficient industrial synthetic process for sacubitril has been developed. Stereoisomers derived from sacubitril and its crucial intermediate have been synthesized, isolated, and characterized for ...