40 mg/kg 151.1 (3.0) 1997.4 (37.6) 362.4 (7.6) 1154.1 (25.2) 20 mg/kg 156.1 (3.8) 602.6 (9.5) 220.0 (8.1) 645.3 (20.9) 10 mg/kg 61.6 (0.3) 274.0 (5.0) 95.2 (1.3) 266.5 (8.5) All doses given by oral ...
Background: The combination therapy of CPT-11, a prodrug of SN-38, with S-1, a dihydropyrimidine dehydrogenase inhibitory fluoropyrimidine, shows a high clinical response rate in non-small cell lung ...
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