引言同样一种蛋白，分散在细胞中，还是聚集成斑点；停留在内质网，还是转运到高尔基体（Golgi apparatus），可能意味着截然不同的生物学状态。但当研究规模扩大到数千万细胞，这些信息往往难以进入遗传筛选。近日，《Cell》的研究报道“SPARCS ...

A new study shows that metabolic stress in insulin-producing beta cells simultaneously remodels Golgi stress proteins, sphingolipid metabolism and lipid droplet regulation, revealing an integrated ...

Every morning, my job was to check on the cells' well-being.I have been researching cells in a laboratory for 22 years.A day ...

A new review argues that the long-overlooked Golgi apparatus, supported by human genetic, proteomic, and lipidomic evidence, may be a central mechanistic hub of Alzheimer's disease and a ...

A new technology promises to enable more comprehensive investigations into how individual genes determine the appearance and ...

The Path to the Birth of MitochondriaInside the cells that make up our bodies, there are small structures called mitochondria ...

Scientists discovered a population of cells that can start the process of programmed cell death, survive it, and then help rapidly rebuild damaged tissue. Their descendants become far more resistant ...

Scientists say they have built a cell from scratch for the first time that can feed, grow and replicate like a natural cell. This breakthrough in synthetic biology could usher in an era of ...

For the very first time, biologists packed nonliving components into a cell-like membrane, piece by piece, and witnessed the bag of molecules start to behave like life. The lab-made synthetic cell ...

Scientists have long dreamed of discovering the alchemy by which chemicals can be turned into life. On Wednesday, a team at the University of Minnesota announced that it had taken a major step toward ...