A new study reveals that astrocytes—star-shaped support cells traditionally viewed as passive partners of neurons—play a ...

A new study reveals that astrocytes—star-shaped support cells traditionally viewed as passive partners of neurons—play a previously underappreciated role in the maturation of coordinated movement. A ...

The production and secretion of VLDLs (very-low-density lipoproteins) by hepatocytes has a direct impact on liver fat content, as well as the concentrations of cholesterol and triglycerides in the ...

Pueblo has long been shaped by railroads, steelmaking, and the movement of goods across the American West. That history gained fresh momentum in 2022 when state legislation formally established the ...

Proinsulin misfolding is central to diabetes. This review examines the cellular mechanisms regulating proinsulin proteostasis in pancreatic β-cells, encompassing genetic factors such as insulin gene ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Live imaging of secretory cargoes is a ...

This month's cover highlights the article RudLOV is an optically synchronized cargo transport method revealing unexpected effects of dynasore by Akiko K. Satoh, Takunori Satoh and colleagues. The ...

A study entitled "IER3IP1-mutations cause microcephaly by selective inhibition of ER-Golgi transport", now published in the open access journal "Cellular and Molecular Life Sciences", provides new ...

In the interests of transparency, eLife publishes the most substantive revision requests and the accompanying author responses. [Editors' note: this paper was reviewed by Review Commons.] Sagia et al.

This important study sheds new light on cargo movement within the Golgi apparatus, challenging the cisternal progression model by providing convincing evidence for a velocity decrease from cis to ...