Gut

Indole-3-propionic acid links gut dysfunction to diabetic retinopathy: a biomarker and novel therapeutic approach

Background Both host and microbe metabolism of tryptophan (Trp) is altered in diabetes; however, the molecular mechanisms are ...
Gut

Oncological impact of universal endoscopic submucosal dissection for large Barrett’s cancers

Background Oncological principles favour en bloc R0 excision for curative endoscopic resection. In Barrett’s neoplasia, ...
Gut

LY6D identifies persistent stem-like cells driving pancreatic tumourigenesis

Background Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterised by remarkable cellular ...
gut.bmj

Treatment of non-constipated irritable bowel syndrome with the histamine 1 receptor antagonist ebastine: a randomised, double-blind, placebo-controlled trial

Correspondence to Professor Guy Boeckxstaens, Department of Chronic Diseases, Metabolism, and Ageing, KU Leuven, Leuven, Belgium; guy.boeckxstaens{at}kuleuven.be Objective We evaluated the histamine 1 ...
gut.bmj

Melatonin improves abdominal pain in irritable bowel syndrome patients who have sleep disturbances: a randomised, double blind, placebo controlled study

Background and aims: Melatonin, a sleep promoting agent, is involved in the regulation of gastrointestinal motility and sensation. We aimed to determine if melatonin was effective in improving bowel ...
gut.bmj

The Asia-Pacific Colorectal Screening score: a validated tool that stratifies risk for colorectal advanced neoplasia in asymptomatic Asian subjects

1 Department of Medicine, National University of Singapore, Singapore, Singapore 2 Department of Internal Medicine, National Taiwan University, Taipei, Taiwan 3 Department of Medicine and Therapeutics ...
gut.bmj

Gut, inflammation and osteoporosis: basic and clinical concepts

1 Christian Doppler Research Laboratory for Gut Inflammation and Department of Medicine, Division of Gastroenterology and Hepatology, Medical University Innsbruck, Austria 2 Department of Medicine “T” ...
gut.bmj

A reproducible grading scale for histological assessment of inflammation in ulcerative colitis

Dr K Geboes, Department of Pathology, University Hospital, KULeuven, Minderbroedersstraat 12, 3000 Leuven, Belgium. Email: Karel.Geboes{at}uz.kuleuven.ac.be BACKGROUND Evaluation of histological ...
gut.bmj

Diffusion-weighted magnetic resonance without bowel preparation for detecting colonic inflammation in inflammatory bowel disease

1 Inserm, U954 and Department of Hepato-Gastroenterology, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France 2 Departement of Radiology, University Hospital of Nancy, Vandoeuvre-lès-Nancy, ...
gut.bmj

Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification

Dr L Lundell, Department of Surgery, Sahlgrenska University Hospital, S-413 45 Göteborg, Sweden. BACKGROUND Endoscopic oesophageal changes are diagnostically helpful and identify patients exposed to ...
gut.bmj

Biomarkers for bile acid diarrhoea in functional bowel disorder with diarrhoea: a systematic review and meta-analysis

3 Division of Preventive Medicine, Department of Internal Medicine, Robert D and Patricia E Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota, USA There is no ...
gut.bmj

Validation of the definition of gastro-oesophageal junctional zone: an immunohistochemical study using resected mucosal specimens

In 2022, the gastro-oesophageal junctional zone (GOJZ) was proposed at the International Consensus Conference in Kyoto as the area extending 1 cm proximally and 1 cm distally from the ...