Cancer Research

First-line Therapy in Newly Diagnosed Multiple Myeloma

AbstractFirst-line multiple myeloma treatment has evolved from melphalan–prednisone to quadruplet regimens incorporating proteasome inhibitors, immunomodulatory drugs, anti-CD38 monoclonal antibodies, ...
Cancer Research

Open Access, Free Access, and Article Archiving

Authors may opt to publish their research under an open access license in any of the AACR hybrid journals. The hybrid AACR journals include: Blood Cancer Discovery; Cancer Discovery; Cancer ...
Cancer Research

Targeting Tumor-Associated Macrophages and Cancer-Associated Fibroblasts to Overcome Therapeutic Resistance in Hepatocellular Carcinoma

1Department of Gastroenterology, Ajou University School of Medicine, Suwon, Republic of Korea. 2BK21 R&E Initiative for Advanced Precision Medicine, Ajou University School of Medicine, Suwon, Republic ...
Cancer Research

Effect Modification by Serum Vitamin A Levels on the Association between Vitamin D and Relapse or Death in Patients with Digestive Tract Cancer

2Department of Gastroenterological Surgery, International University of Health and Welfare Atami Hospital, Shizuoka, Japan.
Cancer Research

Gilead to Spend up to $1.5 Billion on MAT2A Inhibitor

California-based biopharmaceutical company Gilead Sciences signed a licensing deal with China’s Genhouse Bio for the latter’s MAT2A inhibitor GH31. Gilead will pay $80 million up front for worldwide ...
Cancer Research

The Diverse Roles of Lipid Metabolism Reprogramming in Shaping the Tumor Immune Microenvironment

Abstract. Lipid metabolism reprogramming modulates the tumor microenvironment (TME) and alters the function of immune cells, including tumor-infiltrating lymphocytes (TIL). Although lipids can enhance ...