Rivron led the development of the first complete embryo model. It reflects the blastocyst in mice (2018, Nature) and humans (2021, Nature) and is named blastoid. Blastoids are unique in two respects: ...

For the first time, a molecular mechanism is identified, for experimental acceleration and deceleration (rejuvenation) of sperm epigenetic aging.

As a result, cells develop into different cell types and perform a variety of functions. This is especially relevant during ...

Currently, preclinical research relies heavily on laboratory mice, which are nocturnal rodents ... for in vitro -- outside of the body -- embryo culture and manipulation and in vivo -- in the ...

Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...

Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...

Studying human embryonic development is complicated for several reasons. Models derived from pluripotent stem cells ...

The Transgenic and Knockout Core at Mayo Clinic generates transgenic and gene-targeted mice for researchers at Mayo Clinic's campuses in Arizona, Florida and Minnesota. Mouse models are important ...

However, whether BCAS2 has other functions within the nucleus remains largely unknown. Here, we show that BCAS2 is essential for primitive hematopoiesis in zebrafish and mouse embryos. The activation ...

Conservationists said Saturday that they plan to bomb a remote South African island with tons of pesticide-laced pellets to kill mice that are eating albatrosses and other seabirds alive.