Ageing may not simply be the result of damage piling up over time. Scientists studying microscopic worms have discovered a striking structural change inside cells that could play a central role in how ...

A study on worms led by researchers from Vanderbilt University School of Medicine in the US has uncovered a previously unknown adaptation to aging that actively remodels one of the largest and most ...

Yeast, worms, and mice remodel their endoplasmic reticulum early in the aging process. The protective shift offers potential targets to extend healthy lifespan.

The origin of the nucleus remains hotly debated among scientists, but new imaging and genomic data are shedding light on this billion-year-old mystery.

Background Concomitant metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in patients with chronic ...

A secondary stress signaling pathway in the response to optic axon injury is an unexpectedly strong contributor to both neurodegeneration and axon regenerative potential.

Annika Sorenstam is one of the most prolific winners in golf history. She dominated at every level—and is still going. But perhaps even more impressive than wins on her resume was the manner in which ...

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

The lipid metabolism enzyme Ayr1 binds in a substrate-mimicry mechanism to the mitochondrial import (MIM) complex. Unlike typical MIM substrates that are inserted by the MIM complex into the ...