In 1898, Golgi described a special organelle within the cytoplasm of ... revealed the uniqueness and importance of the 'Golgi' apparatus. In 1906, Golgi and Ramón y Cajal 28 obtained the Nobel ...

LRRK2 is mainly a cytoplasmic protein, although also partially associated with membrane organelles ... of actin and microtubule assembly. ER–Golgi transport: overexpression of LRRK2 may promote ...

I have a strong interest in the rough endoplasmic reticulum and, in particular, the translocation apparatus that in this organelle affects the insertion ... that occur in the trans region of the Golgi ...

This can be attributed to monensin being an ionophore. Creating pores in the membranes of the Golgi apparatus disrupts the pH balance of the organelle and prevents enzymes that are active in the ...

Researchers at University of Tsukuba have meticulously examined the gametogenesis of budding yeast, a process involving ...

unpublished). In this study, we investigated the effects of SNARE deficiency on Golgi morphology. We found that the deficiency of SNAREs involved in COPII fusion causes the transformation of Golgi ...

For years, Amanda Smith and her husband were jolted awake at night by a buzz-buzz-beep — an alarm warning that her blood sugar was too high or too low. She would reach for juice boxes stored in ...

Aside from the folding, there is also a sugar chain added to the protein. After these changes, the protein is transported to the Golgi apparatus by a coated vesicle using coating protein COPII. In the ...

Jeffrey D. Gaskin's years of needs-assessment and specification-writing experience means he knows apparatus componentry innovation when he sees it. The recent work of four suppliers particularly ...

Sep. 19, 2024 — Can an immunoassay be created and selectively detect a virus in under 5 minutes? In a new study, researchers report that it can be done using a low-power laser like a laser ...

Electrostatic interactions between the NLRP3 polybasic (PB) region and negatively charged lipids on the trans-Golgi network (TGN) have been proposed to recruit NLRP3 to the TGN. In this study, we ...