Brandon Reagan, a postdoctoral researcher at Michigan State University, explores the relationship between the endoplasmic reticulum and plant stress responses.

Fat-based vesicles help deliver GM1 to the brain, improving movement and extending survival in mouse models of ALS, a study finds.

Spinal cord injury often triggers a cascade of secondary damage that severely limits functional recovery, largely driven by ...

Sepsis remains a major challenge in modern medicine, claiming millions of lives each year. For decades, clinical management has largely focused on suppressing excessive inflammation.

Background Concomitant metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in patients with chronic ...

A researcher at the University of Missouri has made a promising breakthrough in the quest to help people with amyotrophic lateral sclerosis (ALS), the neurodegenerative disorder commonly known as Lou ...

A secondary stress signaling pathway in the response to optic axon injury is an unexpectedly strong contributor to both neurodegeneration and axon regenerative potential.

An international team led by Jaime de Juan-Sanz at the Paris Brain Institute has shown that slightly increasing the metabolic capacity of neurons can enhance long-term memory in both fruit flies and ...

Yeast, worms, and mice remodel their endoplasmic reticulum early in the aging process. The protective shift offers potential targets to extend healthy lifespan.

Ageing may not simply be the result of damage piling up over time. Scientists studying microscopic worms have discovered a striking structural change inside cells that could play a central role in how ...

A buildup of a structural protein called F-actin inside aging brain cells appears to cripple the cellular waste-clearing machinery that keeps neurons healthy, according to a study in Drosophila fruit ...

A study on worms led by researchers from Vanderbilt University School of Medicine in the US has uncovered a previously unknown adaptation to aging that actively remodels one of the largest and most ...