Figure 1: Cryo-EM of dimeric dynein motors bound to MTs in 2 mM Mg-ATP. The structural basis of processive stepping by cytoplasmic dynein has not previously been investigated. Understanding of ...
Cilia are multifunctional organelles that are constructed using intraflagellar transport (IFT) of cargo to and from their tip. It is widely held that the retrograde IFT motor, dynein-2, must be ...
LA JOLLA, CA - Feb. 9, 2018 - On the cellular highway, motor proteins called dyneins rule the road. Dyneins "walk" along structures called microtubules to deliver cellular cargo, such as signaling ...
In a cleverly designed experiment, cell biologists have discovered how dyneins organize chromosome placement to prepare for cell division. The surprise finding suggests it's the motor domain of the ...
What is the dynein-dynactin complex and where is it found? What functions is this molecular motor thought to perform within cells? This is a macromolecular assembly is made up of two components, ...
Cryo-EM reconstruction of dynein's microtubule-binding domain bound to a microtubule and pseudo-atomic model of the complex; micrograph, average of microtubule decorated with dynein's ...
Could studying molecular biology ever be as fun as watching a Star Wars movie? Two scientists decided to create their own science film to entertain viewers, and ended up making new scientific ...
Dr. Jonas Wilson, MD, Ing. Med. Dynein, one of three cytoskeletal motor protein families, was first identified a half century ago and got its name after the ‘dyne’ (i.e. a unit of force). Motor ...
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