New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in ...

The universal features that define genomic regions acting as replication origins remain unclear. In this study, we mapped a set of origins in Trypanosoma brucei using stranded short nascent strand ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

Scientists have found that non-coding 'junk' DNA, far from being harmless and inert, could potentially contribute to the development of cancer. Their study has shown how non-coding DNA can get in the ...

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the ...

BOSTON, Mass. — What if all the information on the internet could be stored in a drop of liquid the size of a quarter? What if billions of copies of that information could be made in minutes? And what ...

A special form of RNA called extra-coding RNA, or ecRNA, controls the careful targeting to add or remove methyl groups to chromosomal DNA of the adult neuron. The ecRNAs are fundamental regulators of ...