A CSF leak within the spinal column is the most common identifiable cause of spontaneous intracranial hypotension. 3 The mechanism underlying headache and neurologic manifestations is presumed to be ...

Inhaled nitric oxide (iNO) has many extrapulmonary effects. As the half-life of nitric oxide (NO) in blood is orders of magnitude less than the circulation time from lungs to the brain, the mediator ...

For many years, the only antemortem clinical laboratory test available for prion disease was limited to the detection of 14-3-3 and total Tau proteins in CSF. As rapid neurodegeneration is a hallmark ...

May aid in the diagnosis of prion disease. RT-QuIC identifies the disease-causing agent. Total TAU and 14-3-3γ are indirect markers of neurodegenerative diseases. Assumes that the patient has a ...

A CSF leak occurs when cerebrospinal fluid (CSF) escapes from the protective layer surrounding the brain and spinal cord. This is a serious condition that can cause headaches, seizures, or meningitis.

After a spinal cord injury, nearby cells quickly rush to action, forming protective scar tissue around the damaged area to stabilize and protect it. But over time, too much scarring can prevent nerves ...