Six of the first seven fights have lines -300 or greater. Here are my predictions for the full UFC 318 card: It’s a trilogy fight in the lightweight division, and Poirier won the first two fights but still enters Saturday as an underdog at home.

Dustin Poirier’s retirement fight at UFC 318 was long in the making. The buildup began with Poirier’s emotional retirement announcement during the 2025 NFL Draft, where he revealed his final fight would take place in his home state of Louisiana,

Perennial fan favorite Dustin Poirier wanted to go home for his farewell and the UFC delivered, putting him in a main event against two-time rival Max Holloway before what's sure to be a partisan crowd at the Smoothie King Center in New Orleans.