The endoplasmic reticulum (ER) is central to protein synthesis, folding and modification, ensuring that the proteome of a cell remains functional and balanced. When the ER is overwhelmed by an ...

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions ...

Calcium (Ca 2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, has not ...

Calcium (Ca 2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, is ...

Brandon Reagan, a postdoctoral researcher at Michigan State University, explores the relationship between the endoplasmic reticulum and plant stress responses.

Endoplasmic reticulum (ER) stress and the unfolded protein response are often implicated in the progression of metabolic dysfunction-associated steatotic liver disease (MASLD), from simple steatosis ...