Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body? There are instances where killer T cells—which are meant to precisely remove virus-infected ...
To make the therapy safer and more adaptable, UChicago researchers developed a new “split” system called GA1CAR. This uses ...
This milestone expands patient eligibility through multi-HLA targetingBuilds on completed TVGN 489 trial demonstrating 100% viral clearance, no ...
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Engineered biomaterial promotes formation of cancer-fighting immune cell clusters
Researchers at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary ...
CAMBRIDGE, MA / ACCESS Newswire / November 3, 2025 / Moderna, Inc. (NASDAQ:MRNA) today announced that the first patient has been dosed in a Phase 1/2 study of mRNA-2808, the Company’s investigational ...
T cell therapies have revolutionized cancer treatment—but so far, their success has been largely limited to blood cancers. Solid tumors, which account for around 90% of all adult cancers, remain a ...
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Study identifies molecular brake that controls overactive killer T cells
Through gene expression analysis, the researchers identified a gene set that increase only in abnormally activated killer T cells induced by IL-15 as markers. They further confirmed that these same ...
A protein notorious for its role in Alzheimer’s disease may hold the key to supercharging the aging immune system, according to new research. Scientists have found that a byproduct of amyloid-beta ...
Once thought to be a flaw in the system, new research suggests that CD4 T cells may actually hold the key to maintaining a properly functioning, age-appropriate immune system. Prof. Alon Monsonego of ...
Cancer immunotherapy, which uses drugs that stimulate the body's immune cells to attack tumors, is a promising approach to ...
According to one of the authors, additional work is needed to validate findings in a larger prospective study ‘and to apply ...
The first patient has been dosed in a Phase 1 trial testing the experimental CAR T-cell therapy obecabtagene autoleucel for progressive MS.
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