ascopubs.org

Plasma levels of SN-38 after co-administration of gefitinib and oral irinotecan in young and old mice

40 mg/kg 151.1 (3.0) 1997.4 (37.6) 362.4 (7.6) 1154.1 (25.2) 20 mg/kg 156.1 (3.8) 602.6 (9.5) 220.0 (8.1) 645.3 (20.9) 10 mg/kg 61.6 (0.3) 274.0 (5.0) 95.2 (1.3) 266.5 (8.5) All doses given by oral ...
The Spruce on MSN

Does Baking Soda Really Get Rid of Mice? We Asked Pest Pros What They Actually Use

Key Points Baking soda can be effective against certain pests, such as insects, but not rodents.Mice need to ingest an enormous amount of baking soda for it to be effective—and it's an inhumane way to ...
The Spruce on MSN

We Asked a Pest Pro for His Go-To Method to Naturally Repel Mice—And It's So Easy

Key Points Peppermint, rosemary, and citronella oils can effectively deter mice for up to 60 days.Once combined, spray along walls and entry points, anywhere where mice travel.Long-term protection ...
ascopubs.org

Synergistic antitumor activity of the SN-38-incorporating polymeric micelles NK012 with S-1.

Inhibition of triple-negative breast cancer (TNBC) and breast cancer stem cells (bCSC) by caffeic acid phenethyl ester (CAPE). Background: The combination therapy of CPT-11, a prodrug of SN-38, with S ...
GEN

Diabetes, Metabolic Syndrome in Mice Treated Using Novel Compound Class

Researchers at Washington University School of Medicine in St. Louis have developed a new class of compounds that can improve multiple aspects of metabolic syndrome. The compounds act as modulators of ...
EurekAlert!

Diabetes, metabolic syndrome in mice treated with novel class of compounds

image: Researchers at Washington University School of Medicine in St. Louis have shown, in mice, that a new class of compounds they developed can improve several aspects of metabolic syndrome. Such ...