Reactive oxygen species (ROS) production by NADPH oxidase (NOX) is a key promoter of platelet activation, making NOX inhibition an attractive antiplatelet strategy. This study evaluated the effects of ...

Colchicine is well known as an anti-inflammatory drug used in the treatment of acute gouty arthritis, familial Mediterranean fever and Behçet’s disease 1. Additionally, it has been used for the ...

Despite being acaryote cell fragments, platelets share a number of properties of host defense with their big nucleated relatives and represent important elements in innate immunity. For these purposes ...

A research team led by Professor Koji Eto revealed that disruptions of the KCNN4 potassium channel impair mitochondrial function and cytoskeletal organization in megakaryocytes, leading to reduced ...