The overdose-reversing drug naloxone has been rightly hailed as a lifesaving breakthrough, saving countless lives from opioid ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a ...

The search for a safer opioid has followed pain medicine for decades. Doctors still need strong drugs for surgery, major ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 16 (April 19, 2022), pp. 1-10 (10 pages) Allosteric modulators of G-protein-coupled receptors (GPCRs) ...

Last week, researchers dropped a bombshell report on DFNZ, a developing new medicine derived from a class of drugs once ...

Given how profound an influence opioids have on the world – for better or worse – scientists know surprisingly little about how these drugs actually work. A recent study led by researchers from ...

Neuropeptide FF (NPFF) is an endogenous peptide that plays a critical role in modulating opioid receptor function. Its dual capacity to influence both opioid-induced analgesia and tolerance has ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...

Muse Treatment Alcohol & Drug Rehab Los Angeles has published a new educational resource that explains how opioid receptors function in the brain and why they play a central role in pain relief, ...

New research led by UCLA Health has found a drug that treats insomnia works to prevent the addictive effects of the morphine opioids in mice while still providing effective pain relief. At high doses ...

President Trump signs a monumental executive order fast-tracking psychedelics for mental health treatment, and ibogaine is ...