Adding Pluvicto to standard therapy in metastatic patients led to a radiographic PFS benefit, but questions remain about whether the agent belongs in the first-line setting.

Screening for prostate cancer becomes more complex in men over the age of 70. The US Preventive Services Task Force (USPSTF) currently recommends against routine PSA testing in this age group. The PSA test measures the level of prostate-specific antigen in the blood,

Targeting prostate-specific membrane antigen, Lu-PSMA-617 has demonstrated clinical benefits in patients with PSMA-positive mCRPC after progression on ARPIs, including patients with and without prior taxane treatment. PSMA-Add was the first phase III trial to target PSMA in mHSPC.

In a significant policy reversal, the National Institute for Health and Care Excellence (NICE) has recommended abiraterone for adults with newly diagnosed high-risk metastatic prostate cancer, following a reassessment prompted by the availability of lower-cost generic versions.

When prostate cancer spreads beyond the prostate gland to other parts of the body, it becomes what medical professionals call metastatic prostate cancer. This advanced form of the disease represents a significant shift in both symptoms and treatment ...

Sept. 18, 2025 -- About 1 in 8 men will face a prostate cancer diagnosis. Early-stage prostate cancer often has no symptoms—so how should men approach screening and advocacy? What disparities do Black men experience that would negatively impact their ...

Zoledronic acid reduced fracture risk by 27% in men with metastatic prostate cancer receiving ADT in the STAMPEDE trial. Patients with non-metastatic disease showed no significant fracture benefit from bisphosphonate treatment. Overall fracture incidence ...

CNN — (CNN) — President Joe Biden’s diagnosis of metastatic prostate cancer has understandably raised concerns and questions: How long has he had cancer, how will he be treated, and what is his prognosis? As a urologist, I regularly diagnose prostate ...