Craniofacial development is a complex process that involves the specification of diverse and transient cell types. However, our understanding of these processes and the cell-types present during human ...
Translating genome-wide association study (GWAS) loci into causal variants and genes requires accurate cell-type-specific enhancer–gene maps from disease-relevant tissues. Building enhancer–gene maps ...
Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...
The Joint Open Genome and Omics Platform 1.0 (JoGo 1.0) catalogs 19,194 human genes with a novel naming system. Researchers expect the database to benefit medicine and genomics, and to provide a ...
A detailed cellular study of Crohn's disease has mapped how gene activity changes across more than 50 cell types in the gut.
Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...
Earth’s biodiversity is in crisis. An imminent “sixth mass extinction” threatens beloved and important wildlife. It also threatens to reduce the amount of genetic diversity – or variation – within ...
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