Parts of the distal nephron have specific salt transporters, which are the main targets of medicine's most effective diuretics, used in the treatment of hypertension and chronic kidney disease. Thus, ...

“You’re on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can’t handle it. You’re harming them.” ...

Circulating blood is filtered across the glomerular barrier to form an ultrafiltrate of plasma in the Bowman’s space. The volume of glomerular filtration adjusted by time is defined as the glomerular ...

Congenital anomalies of the kidney and urinary tract encompass a broad spectrum of developmental defects that may affect nephron number, renal architecture and urinary outflow. Reduced nephron ...

The kidney carries out important functions via microscopic functional units called nephrons. Researchers are investigating which factors control the formation and function of specific segments of the ...