Nature

Inhibition of apoptosis signal-regulating kinase 1 enhances endochondral bone formation by increasing chondrocyte survival

Endochondral ossification is the result of chondrocyte differentiation, hypertrophy, death and replacement by bone. The careful timing and progression of this process is important for normal skeletal ...
The New England Journal of Medicine

C-Type Natriuretic Peptide Analogue Therapy in Children with Achondroplasia

Achondroplasia is a genetic disorder that inhibits endochondral ossification, resulting in disproportionate short stature and clinically significant medical complications. Vosoritide is a biologic ...
JSTOR Daily

Constitutive Activation of MKK6 in Chondrocytes of Transgenic Mice Inhibits Proliferation and Delays Endochondral Bone Formation

Accumulating in vitro evidence suggests that the p38 mitogenactivated protein kinase (MAPK) pathway is involved in endochondral ossification. To investigate the role of this pathway in endochondral ...
JSTOR Daily

Critical Roles of the Guanylyl Cyclase B Receptor in Endochondral Ossification and Development of Female Reproductive Organs

Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, No. 49 (Dec. 7, 2004), pp. 17300-17305 (6 pages) Guanylyl cyclase B is the receptor for a small peptide ...