Conversion of IgG antibodies to IgM broadens antibacterial activity

Researchers at UMC Utrecht have discovered that converting monoclonal antibodies from the IgG to the IgM isotype can ...
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Biohaven Reports Positive Degrader Data Achieving > 80% Sustained Reductions in Total IgG with Potential First-in-Class BHV-1300

Optimized subcutaneous administration of BHV-1300 achieved rapid, deep and sustained lowering of IgG, differentiating Biohaven's (BHVN) new small molecule class of degraders from the monoclonal ...