Discover how early optimization in stable cell line development accelerates timelines and reduces downstream bottlenecks.

What are the first steps that chart the path for a cell to become a blood cell, neuron cell, or pigment cell? Scientists have developed increasingly powerful tools to track those changes, but one ...

Successfully producing large quantities of biotherapeutics, including monoclonal antibodies and recombinant protein products, depends on robust and reliable cell line development (CLD). Issues that ...

About 9% of men of reproductive age in the United States experience fertility problems. One of the many causes of male infertility is a failure in germline development, the process by which embryonic ...

The development of humans and other animals unfolds gradually over time, with cells taking on specific roles and functions via a process called cell fate determination. The fate of individual cells, ...

As an embryo develops from a small cluster of stem cells, those once "blank slate" cells begin to take on more specialized ...

A new cellular atlas charts, in unprecedented detail, how human B cells are built step by step — and offers a window into how this developmental process goes awry in leukemia. The KAUST-led ...

Researchers from the Center for Regenerative Medicine (CReM) and the Department of Medicine at Boston Medical Center (BMC) and Boston University (BU) have made a breakthrough that holds promise for ...

A 'pocket' on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Cell division is key for life. Every organism -- from the smallest yeast ...