If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic ...

Intracellular DNA can become damaged and/or distorted through a multitude of endogenous and exogenous sources (e.g., post-replication mismatches, base oxidation, cyclobutane pyrimidine dimers) 1,2.

Scientists assess bacterial growth trajectories to better predict infectious capacity and the conditions that aid proliferation. This article explores the key factors that influence bacterial ...

E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...

Red arrows indicate the DNA repair pathways that are known to aid bacterial survival as persisters and gamblers in the presence of fluoroquinolones. Blue color arrow indicates downregulation, while ...

Top: Chromosome separate with functioning SMC in two models, line drawing and filled-space. The red and pink dots indicate, respectively, ori on each copy of DNA. Bottom: DNA separating without ...